Somatostatinoma

 

 

 

Somatostatinoma is a tumor of the delta cells of the endocrine pancreas that produces somatostatin.

 

 It is associated with diabetes mellitus and abnormal glucose tolerance.

 Triad of : Mild Diabetes Mellitus, Steatorrhoea, Gall stones.

 Commonly found in head of pancreas, and are malignant.

 Elevated plasma levels of Somatostatin.

 Treatment is by chemotherapy with streptozocin, dacarbazine, doxorubicin.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

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